Mechanism of Action

Mupirocin exerts its action by reversibly binding to isoleucyl transfer RNA synthetase and inhibits the enzyme activity. This enzyme is necessary for the synthesis of proteins in the bacteria. Inhibition of isoleucyl transfer RNA synthetase results in inhibition of protein synthesis and produce microbicidal action.

Beclomethasone:It inhibits synthesis of prostaglandin and leukotrines which is responsible for pain and inflammatory response

Adverse Drug Reaction

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Most common effects are:

• Burning, stinging or pain on the application site
• Itchy and dry skin

Dose

• Use the ointment twice or three times a day for 1 to 2 weeks or consult with doctor

Precautions

• Use it on all the affected areas.
• If you use it twice a day, try to leave a gap of 8 to 12 hours between doses.
• Generally use upto 1 week, contact your doctor if it does not improve within 2 to 4 weeks (or 5 days for a child or when using it on your face).
• Avoid any contact with your eyes, nose or mouth.

Contraindications

• Allergic reaction to Beclometasone and/or Mupirocin in the past
• Acne or rosacea

Pregnancy and Breast Feeding

• Do not use this medication if you are pregnant and planning to get pregnant.
• Do not use this medication if you are Breast feeding

Presentation

5 gm Tube