PHARMACOLOGY

Pharmacotherapeutic Group: Topical Analgesic and Anti-inflammatory Preparation

 Diclofenac:

Diclofenac, a phenylacetic acid derivative is a prototypical NSAID. It has potent anti-inflammatory, analgesic and antipyretic actions. It reversibly inhibits the enzyme, cyclooxygenase, thus resulting in reduced synthesis of prostaglandin precursors.

 Methyl Salicylate:

Methyl Salicylate is a rubefacient. It produces reddening of the skin by the dilation of the blood vessels and gives a soothing feeling of warmth. It is also called as counter irritant as it produces its action by counter irritation.

 Linseed Oil:

The Omega-3 found in Linseed Oil is a naturally occuring antiinflammatory agent. It inhibits arachidonic acid induced inflammation.

 INDICATIONS

Rheumatoid arthritis, Ankylosing spondylitis, Tendonitis, Bursitis, Sprain, Strain, Lumbago, Sports injury, Muscular Pain, Neck Pain, Frozen shoulder, Wrist pain

 DOSAGE & ADMINISTRATION

Apply in the affected area 3-4 times daily.

 ADVERSE DRUG REACTIONS

Application site dermatitis, pruritus, erythema, paresthesia, dryness, irritation.

 PRECAUTIONS

Salif Emulgel should not be applied to open skin, wounds, infections, inflammation or exfoliative dermatitis as it may affect absorption and tolerability of the drug. Salif Emulgel should not be allowed to come into contact with the eyes or mucus membranes.

 CONTRAINDICATIONS

Patients with known hypersensitivity to diclofenac.

 PRESENTATION

SALIF Emulgel: Each tube contains 30gms of Emulgel