Generic Name


Therapeutic Category



Cefdinir 125mg Dispersible Tablets

Cefdinir 250mg Dispersible Tablets

Cefdinir 300mg Tablets

Cephalosporin Antibiotic


     DINIR 125mg   Each dispersible tablet contains:
     Cefdinir           125mg
    DINIR 250mg  Each dispersible tablet contains:
     Cefdinir            250mg
    DINIR 300mg Each tablet contains:
     Cefdinir            300mg

    Cefdinir binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.


    Absorption: Oral Bioavailability- Maximal plasma cefdinir concentrations occur 2 to 4 hours postdose following capsule or suspension administration. Following administration of suspension to healthy adults, cefdinir bioavailability is 120% relative to capsules. Estimated bioavailability of cefdinir capsules is 21% following administration of a 300 mg capsule dose, and 16% following administration of a 600 mg capsule dose. Estimated absolute bioavailability of  cefdinir suspension is 25%.

    Distribution:The mean volume of distribution (Vdarea) of cefdinir in adult subjects is 0.35 L/kg (±0.29); in pediatric subjects (age 6 months-12 years), cefdinir Vdarea is 0.67 L/kg (±0.38). Cefdinir is 60% to 70% bound to plasma proteins in both adult and pediatric subjects; binding is independent of concentration.

    Mean skin blister concentrations  were 48% of corresponding plasma concentrations, Mean tonsil tissue concentrations were 24% of corresponding plasma concentrations, Mean sinus tissue concentrations were 16% of corresponding plasma concentrations., Mean epithelial lining fluid concentrations 35% of corresponding plasma concentrations, Mean middle ear fluid concentrations were 15% of corresponding plasma concentrations

    Metabolism and Excretion: Cefdinir is not appreciably metabolized. Activity is primarily due to parent drug. Cefdinir is eliminated principally via renal excretion with a mean plasma elimination half-life (t½) of 1.7 (±0.6) hours


    Pneumonia, Bronchitis, Otitis Media, Tonsillitis/ Pharyngitis, Sinusitis, Skin & Structure Infection


    The recommended dose for Cefdinir in children is 7mg/kg twice daily or 14mg/kg once daily and for adult is 300mg twice daily for 5-10 days.

    Side effect

    Diarrhea, rash, vomiting, oral thrush, abdominal pain, vaginitis or vaginal moniliasis or leukopenia


    Hypersensitivity to cephalosporin.

    Special Precaution

    Penicillin-sensitive patients; superinfection; seizure; pseudomembranous colitis; pregnancy, lactation; renal insufficiency.

    Drug Interaction

    Concomitant admin with antacids and Fe reduce the rate and extent of absorption, Probenecid reduces renal elimination and Antacids reduce rate and extent of absorption


    DINIR 125mg DT: Each box contains 10 Strips of 10 Tablets

    DINIR 250mg DT: Each box contains 10 Strips of 10 Tablets

    DINIR 300mg Tab: Each box contains 10 Strips of 10 Tablets


    Pregnancy:   Category B

    Labor and Delivery
    Cefdinir has not been studied for use during labor and delivery.
    Nursing Mothers
    Following administration of single 600-mg doses, cefdinir was not detected in human
    breast milk.

    Storage:  Store in a cool and dry place; Protect from light, heat and moisture; Keep away from the reach of children.

    • Missed dose: Take the missed dose as soon as you remember
    • Skip the missed dose if it is almost time for your next scheduled dose
    • Do not take extra medicine to make up the missed dose.