Absorption of adapalene through human skin is low. Only trace amounts (
METABOLISM
Metabolized mainly by O-demethylation, hydroxylation and conjugation, and excretion are primarily by the biliary route.
ROUTE OF ELIMINATION
Excretion appears to be primarily by the biliary route.
ADVERSE DRUG REACTION
Side effects include erythema, dryness, burning, scaling, and photosensitivity.
PREGNANCY: Category C
HOW TO APPLY
- Gently clean the affected areas, using a mild cleanser and pat dry.
- Apply this product once a day, and apply it at the same time each day.
- Apply as a thin layer to the affected areas.
- Avoid contact with eyes, lips and mouth. If contact occurs, immediately flush the area with water.
- Do not apply the product to damaged skin i.e cuts, burns, abrasions, eczema, and sunburn.
- Wash hands after use.
