PRODUCT DETAILS

Product Lists

DAPLIN-C

Description & Professionals

Generic Name

Composition

Therapeutic Category

Division

Adapalene + Clindamycin

0.1 % w/w Adapalene + 1 % w/w Clindamycin

Anti-Acne

COSMO

    Generic Name: Adapalene + Clindamycin
    Strength: 0.1 % w/w Adapalene + 1 % w/w Clindamycin
    Class of Drug : 3rd Generation of Topical Retinoid + Macrolide Antibiotic
    Therapeutic Class : Anti-Acne 
    Packaging Size : 10 gm Tube 

     INDICATION : Acne Vulgaris

    MECHANISM OF ACTION   : Adapalene binds to specific retinoic acid nuclear receptors of skin and lead to normalization of keratinocyte differentiation allowing for decreased micro-comedone formation, decreases clogging in pores and gives exfoliative properties by increasing cell turnover. Adapalene also shows anti-inflammatory effect by inhibition lipo-oxygenase activity. Clindamycin inhibits protein synthesis of bacteria (P. acnes) which causes infection on the acne lesions, by binding to 50S ribosomal subunit thus kills bacteria.

    ADVERSE DRUG REACTION 
    Include dry skin, irritation of the skin, scaling  and redness
     
     CONTRAINDICATION 
    In patient with Hypersensitivity to Any ingredients. In patients who have history of acute eczema, rosacea and perioral dermatitis.
     
    PREGNANCY & LACTATION 
    Should not be given/used during pregnancy and breast feeding.

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