Generic Name


Therapeutic Category



Rifaximin 550 mg Tablets

Rifaximin 200 mg Tablets

Rifamycin Antibiotic


    Brand Name: Ribet

    Generic: Rifaximin

    Composition: Rifaximin 550 mg & 200 mg Tablets

    Therapeutic Category: Antibiotic

    Mechanism of action:

    • Antimicrobial action is a result of binding to the beta-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of transcription

     Hepatic encephalopathy: Inhibits growth of enteric ammonia-producing bacteria to indirectly reduce serum ammonia level

     Irritable bowel syndrome with diarrhea: The exact mechanism of action for IBS-D is not known, but is thought to be related to changes in the bacterial   content in the gastrointestinal tract and reduction of gas



    Bioavailability: <0.4%, Peak plasma time: 1 hr


    Gut: 80-90%


    Induces CYP3A4 in hepatocytes in vitro


    Half-life: 2-5 hr, Excretion: Feces (>90%)

    Indication & Dosing:



    Hepatic Encephalopathy in adult

    550 mg twice daily

    Traveler’s Diarrhea by noninvasive strains of E. coli (>12 years)

    200 mg thrice daily  for 3 days

    Irritable Bowel Syndrome with diarrhea (IBS-D) in adult

    550 mg thrice daily  for 14 days;recurrence of symptoms can be retreated with the same regimen upto 2 times

    Ribet can be taken with or without food

    Pregnancy Category: C

    Lactation: Use not recommended

    Side Effects: Flatulence, Headache, Rectal tenesmus, Abdominal pain, Defecation urgency 

    Cautions: Not effective in diarrhea complicated by fever, hematochezia, or diarrhea due to pathogens other than Escherichia coli

    Missed Dose: Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


    • Ribet 550 Each box contains: 10 strips X 10 Tabs. ALU-ALU Packing
    • Ribet 200 Each box contains: 10 strips X 10 Tabs. ALU-ALU Packing