PHARMACOLOGY 

Pharmacotherapeutic Group: Cough Preparation (Productive Cough)

Terbutaline Sulphate: Terbutaline is a bronchodilator; a medication that dilates (expands) air passages in the lungs. It attaches to beta adrenergic receptors on muscles surrounding the air passages, causing the muscles to relax and dilate the air passages. Wider air passages allow more air to flow in and out of the lungs.

Pharmacokinetics:

• Protein binding 25%
• Metabolism GI tract (oral), liver; CYP450: unknown
• Elimination half-life 11–16 hours
• Excretion urine 90% (60% unchanged), bile/faeces

Bromhexine HCl: Bromhexine acts on the mucus at the formative stages in the glands, within the mucus-secreting cells. Bromhexine disrupts the structure of acid mucopolysaccharidefibres in mucoid sputum and produces less viscous mucus, which is easier to expectorate.

Pharmacokinetics: 

• Bioavailability 75–80%
• Elimination half-life 12 hr

INDICATIONS

Productive Cough associated with Bronchitis, Bronchial asthma, Emphysema, Broncho-Pulmonary disorder

DOSAGE & ADMINISTRATION

• Drink plenty of fluids while taking PULMARIN-X to loosen mucus.
• It can be taken with or without food as advised by your doctor with the help of a measuring cup (available at phial).
• If you use it twice a day, try to leave a gap of 8 to 12 hours between doses.

ADVERSE DRUG REACTIONS

Nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremor, nervousness, diarrhoea and fast heartbeats.

PRECAUTIONS

PULMARIN-X should be used with caution in patients with allergic on ingredients, epilepsy/seizures, diabetes, high blood pressure, thyroid problems.

CONTRAINDICATIONS

• Not recommended for children below 6 years of age and body weight less than 25 kg.
• Not recommended for dry cough (unproductive cough).

PRESENTATION

• PULMARIN-X: Each bottle 100ml of Syrup
• PULMARIN-X Pead.: Each bottle 60ml of Syrup