Generic Name

Composition

Therapeutic Category

Division

Beclomethasone + Clotrimazole + Gentamicin Sulphate

Beclomethasone 0.025% w/w + Clotrimazole 1% w/w + Gentamicin Sulphate 0.1% w/w Cream

Anti-infective / Anti-inflammatory

TIME

    BRAND COMPOSITION DESCRIPTION
    BECLOTIME

    Beclomethasone Dipropionate IP                 0.025% w/w

    Gentamicin Sulphate equivalent to Gentamicin       0.1%w/w

    Clotrimazole IP                                  1% w/w

    White semisolid cream. 15 g of the cream filled in a collapsible aluminum tube.
     

    PATIENT INFORMATION

    PATIENT INFORMATION

    Administration:Gently massage sufficient amount of cream into the affected and surrounding skin areas

    Pregnancy: Category C

    Storage:Store between 2oC and 30oC. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it in cool & dark place. DO NOT FREEZE.

    Missed Dose:If you forget to apply the cream, apply it as soon as you remember; If your next dose is due within an hour, skip the missed dose; Do not use a double dose to make up for a forgotten dose.

     


    PHARMACOLOGY

    Beclomethasone is a potent corticosteroid. After topical application it produces anti- inflammatory and vasoconstrictor effects and is used for reducing the inflammation of the skin. The antiinflammatory action of beclomethasone is because it controls the biosynthesis of prostaglandin and leukotrienes, the potent mediators of inflammation.

    Clotrimazole inhibits the fungal cell wall synthesis by interfering action of enzyme 14-α demethylase.

    Gentamicin is a broad spectrum aminoglycoside antibiotic. It works by binding to the bacterial 30s ribosomal subunit, causing misreading of t-RNA and inhibits the bacterial protein synthesis.

     

    INDICATIONS

    Allergic dermatitis, Pruritus, Eczema, Napkin rashes, Athelet's foot, Burns

     

    DOSAGE & ADMINISTRATION

    Apply Beclotime cream once or twice daily.

     

    ADVERSE DRUG REACTIONS

    Loss of skin collagen, local hypopigmentation of deeply pigmented skin dryness, irritation

     PRECAUTIONS

    Pregnancy, lactation

     CONTRAINDICATIONS

    Hypersensitivity, acute infections uncontrolled by antimicrobial chemotherapy

     PRESENTATION

    BECLOTIME: Each tube contains 15g cream