Time Pharmaceuticals

Description
Professionals

Generic Name

Composition

Therapeutic Category

Division

Clotrimazole

Clotrimazole 1% w/w Cream

Anti-fungal

COSMO

BRAND	COMPOSITION	DESCRIPTION
CLOTIME	Clotrimazole IP 1% w/w	15 g of white semisolid cream filled in a collapsible aluminum tube.

PATIENT INFORMATION
Administration: CLOTIME cream is for external use only and should not be put in the mouth or swallowed. Do not use the cream to treat nail or scalp infection. If the feet are affected they should be washed and dried thoroughly especially between the toes before applying the cream. Pregnancy: Category B Storage: Store between 2-30°C. Keep out of reach of children. Missed Dose: If you miss a dose use it as soon as you remember; If it is near the time of next dose skip the missed dose and resume your usual dosing schedule; Do not double the dose to make up the missed dose.

PATIENT INFORMATION

Administration:

CLOTIME cream is for external use only and should not be put in the mouth or swallowed.
Do not use the cream to treat nail or scalp infection.
If the feet are affected they should be washed and dried thoroughly especially between the toes before applying the cream.

Pregnancy: Category B

Storage: Store between 2-30°C.

Keep out of reach of children.

Missed Dose: If you miss a dose use it as soon as you remember; If it is near the time of next dose skip the missed dose and resume your usual dosing schedule; Do not double the dose to make up the missed dose.

PHARMACOLOGY

Pharmacotherapeutic Group: Antifungal agent

Pharmacodynamic properties: CLOTIME (Clotrimazole) acts against fungi by inhibiting 14α demethylase enzyme thus prevent the conversion of lanosterol to ergosterol. Inhibition of ergosterol synthesis leads to structural and functional impairment of the fungal cytoplasmic membrane.

Pharmacokinetic properties: Minimally absorbed from intact or inflamed skin into human blood circulation.

INDICATIONS

Superficial candidiasis; Oral thrush; Athlete's foot, Vaginal yeast infection; Jock itch

DOSE

Apply 2-3 times daily in affected area for 2-4 weeks. Treatment should be continued for atleast1month for dermatophyte infection and at least 2 weeks for candida infection.

CONTRAINDICATIONS

Hypersensitivity

SPECIAL PRECAUTIONS

Pregnancy and lactation; Use of rubber contraceptive (reduce the effectiveness)

ADVERSE DRUG REACTIONS

Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis

DRUG INTERACTIONS

Antagonism with polyene antibiotics.

PRESENTATION

CLOTIME: Each tube contains 15g of cream

PRODUCT DETAILS

Product Lists

CLOTIME

Description & Professionals

PATIENT INFORMATION